Hemoglobin is found in red blood cells---the highest number of cells in the blood. It is a key component for red blood cells to transport oxygen and a part of carbon dioxide. Red blood cells are produced from the bone marrow and enter the blood after maturation. After aging, they return to the bone marrow voluntarily to wait for the white blood cells to destroy and recast. Or it is broken down by macrophages when passing through the liver and enters the bile.
Hemoglobin is mainly composed of protein part, ferrous ions, and porphyrin (above). The synthesis of porphyrin requires folic acid and methylcobalamin (endogenous vitamin B12), and the synthesis process requires a lot of energy. Therefore, malnutrition Or the relative lack of key nutrients for the synthesis of hemoglobin (including too many tumors, treatment side effects caused by dietary digestion and absorption problems, etc.), will cause the decline of hemoglobin, follow-up age increases, bone marrow hematopoietic function decline, tumor invasion of bone marrow will also, Of course, the side effects of chemotherapy (inhibition of bone marrow hematopoietic function), bleeding, and many common congenital or acquired blood diseases can also cause a decrease in hemoglobin-Anemia.